A: Take Duralast at least 1–3 hours before anticipated sexual activity.
A: Studies tell, after three months of men taking 30 mg dose of dapoxetine took an average 2.78 minutes to ejaculate after penetration.
A: There is no permanent cure for premature ejaculation (PE), but there are treatments that can help. Some treatments include medications, counselling and techniques.
A: No. Duralast is not recommended for use in patients with heart problems (such as a heart attack or abnormal heart rhythm).
A: Duralast should be used with caution in patients with kidney diseases.
Viagra enhances blood flow to the penis, which helps in achieving and sustaining an erection. Dapoxetine helps to delay ejaculation by increasing serotonin levels in the brain, which improves control over the timing of ejaculation.
A: Consult your doctor before taking Duralast and Viagra together, as they may lower your blood pressure, especially when standing up.
A: Duralast should only be used if you are diagnosed with premature ejaculation. It is not intended for regular daily use.
A: Duralast is not recommended if you are allergic to it, men who are below 18 years or above 65 years. It is not intended for use in women. Avoid consuming alcohol as it might cause increased dizziness.
A: The mean half life of dapoxetine after a single dose was estimated using modelling as 1.3–1.5 hours.
A: Take dapoxetine exactly as instructed by your doctor. Drink a full glass of water at the same time as you take a tablet.
A: Dapoxetine is available at 2 different strengths such as 30 mg and 60 mg. The recommended starting dose for all men is 30 mg, taken as needed approximately 1 to 3 hours prior to sexual activity.
A: Dapoxetine is used for premature ejaculation (PE) in men between 18 to 64 years old.
A: Men taking a 30 mg dose of dapoxetine took an average 2.78 minutes to ejaculate after penetration, those on a 60 mg dose took 3.32 minutes.
A: Men release quickly due to premature ejaculation, nervousness of being with a new partner, anxiousness of having sex again after a long period of abstinence, lack of confidence, guilt, being overly excited or stimulated or other reasons.
Add more control to your time with dapoxetine man who is prescribed dapoxetine 30 mg man who is time with dapoxetine man who is prescribed dapoxetine 60 mg man.Keep in mind, that while dapoxetine is effective in delaying ejaculation there are potential side effects that may be caused by increasing timing of ejaculation.Dapoxetine is an anxiolytic (anti-depressant) medication commonly used to treat premature ejaculation (PE) and premature ejaculation-related sexual dysfunction (PE/PDD), among others. The objective of this study was to investigate the efficacy of dapoxetine in the treatment of PE/PDD in China.
This was a randomized, double-blind, placebo-controlled study. We included 9 patients with PE or PE/PDD who received dapoxetine (25 mg) in a dose of 60 mg orally, for 12 weeks. The patients were asked to take an initial sexual stimulus and to receive sildenafil (40 mg) on a daily basis for a week before the study. The study was conducted according to the principles of the Declaration of Helsinki.
In the study, the incidence of PE/PDD was significantly higher in patients with PE/PDD than in those with PE/SAD. The number of PE/PDD-related events was significantly higher in the group receiving dapoxetine compared with those receiving placebo (P=0.021).
The efficacy of dapoxetine was significantly superior for the treatment of PE/PDD in China. This study suggests that dapoxetine could be considered as a novel therapeutic option for the treatment of PE/PDD in China.
Citation:Zhou Y, Wu Y, Liu D, Jiang Y, Zeng L, Jiang H, Zhang J, et al. (2020) Dapoxetine for the treatment of premature ejaculation in China: A randomized, double-blind, placebo-controlled, clinical study. PLoS ONE 18(10): e02575. https://doi.org/10.1371/journal.pone.025751
Editor:Nadia Bhattacharjee, National Institute for Clinical Excellence, China
Received:August 13, 2020;Accepted:June 16, 2020;Published:July 28, 2020
Copyright:© 2020 Zhou et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Data Availability:The data that support the findings of this study are available from the corresponding author, but the data that support the results are only available upon request.
Funding:The authors received no specific funding for this work.
Competing interests:The authors have declared that no competing interests exist.
The prevalence of premature ejaculation (PE) and premature ejaculation-related sexual dysfunction (PDD) has increased significantly in recent decades []. Among them, PE and PPDD are frequently associated with significant distress and impairment, and both can have devastating effects on daily lives [, ].
PE is the most common sexual disorder affecting approximately 20% of men worldwide, and a major cause of PE in China is premature ejaculation. In the United States, the prevalence of PE is estimated at 6.7% []. PE is common among young men and can cause substantial distress due to poor oral hygiene and psychological problems []. PE is defined as a persistent or recurrent inability to achieve orgasm after ejaculation. The global prevalence of PE is estimated to increase from 6.7% in 2012 [], and it has been reported that 30% of men experience PE in their lifetime [].
Dapoxetine, a selective serotonin reuptake inhibitor (SSRI) is a medication commonly used to treat PE and PE/PDD in China. The most common indications for dapoxetine use in China are anxiety and depression [].
Although the efficacy and safety of dapoxetine in the treatment of PE/PDD have not been extensively studied, it has been reported that dapoxetine is superior to sildenafil in the treatment of premature ejaculation in both clinical and epidemiological studies. A meta-analysis of the efficacy and safety of dapoxetine in the treatment of PE/PDD in China was carried out by Zhang et al. in 2015 [].
Product details
Dapoxetine is an antidepressant used to treat premature ejaculation in men. Premature ejaculation is when a man ejaculates with ejaculatory delay with his ejaculatory being decreased or stopped suddenly with the sexual stimulation. It is used to treat the few minutes before sexual intercourse, and the time it takes for both ejaculators to become sexually excited or stimulated.
Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) drug. SSRIs work by supplementing the levels of serotonin in the brain, which may increase the chances of a positive or a negative reaction. Dapoxetine may also increase the chances of a positive reaction, and if you take it with other SSRIs, you may feel similar changes, but this may not be the same as causing premature ejaculation. Dapoxetine is a short-acting SSRI that you can give orally to men who are at risk of, and you can take for up to 4 hours after giving the prescription to you.
Serotonin is a chemical, which is a key neurotransmitter for which Dapoxetine is used. Dapoxetine, a short-acting SSRI, can increase serotonin levels by blocking its reabsorption in the brain. This allows serotonin to be available for use in the treatment of premature ejaculation, and may also help you pass on sexual activity to your partner, and help you to have a better experience with both you.
Using Dapoxetine may increase the risk of suicide in men
If you think you may be at risk, or if you think you may have a medical condition, conditions, or treatment for which taking Dapoxetine may increase the risk of suicide or suicide-related problems, seek medical advice before having any surgery, including dental work.
Dapoxetine is a short-acting SSRI, and it passes into breast milk in small amounts. However, it may not be used by men who are breastfeeding as it may be passed on during pregnancy and possibly during breastfeeding. Dapoxetine passes into breast milk, but this does not mean it is for use in women.
Dapoxetine has not been studied for its effects on men who use SSRIs such as Thomas Hales and Sirositoriesius, but you may reduce your risk of meningitis in patients taking Dapoxetine by taking a different medicine.
Dapoxetine has not been studied for its effects on women, and men should avoid using it while having vaginal, men's, or pelvic surgery, and if you are breast-feeding, and it is you to take Dapoxetine.
Dapoxetine is a fluoroSSRI drug. It works by replacing the balance of serotonin in the brain, which may increase the chances of a positive or a negative reaction.
It may also increase the risk of a positive reaction, and if you take it with some other fluoroSSRIs, you may feel similar changes, but this may not be the same as having Premature Ejaculation.
Dapoxetine is a short-acting SSRI such asotonin. It passes into breast milk in small amounts. It may also be passed on during pregnancy and may sometimes do so before your baby has been born.
Dapoxetine has not been studied for its effects on men who use short-acting SSRIs such as Thomas Hales, and it may not be used by men who are breastfeeding. It has been studied for its effects on Premature Ejaculation in women, but it may not be used by men who are planning to have intercourse during surgery.
Sildenafil Citrate 100mg Tablets is a medicine that is commonly used to treat erectile dysfunction (impotence). It helps to achieve and maintain an erection for satisfactory sexual activity in men. This drug helps increase blood flow to the penis to help a man get and keep an erection. It is available in the form of a tablet or a disintegrating pack that is easy to swallow. When taking sildenafil 100mg Tablets, you can control the effects of sexual stimulation by increasing the blood flow to the penis. You should not use this medicine if you have certain medical conditions such as:
Sildenafil Citrate 100mg Tablets are used to treat erectile dysfunction (impotence) in men by increasing blood flow to the penis during sexual stimulation. This medicine works by blocking the effects of certain chemicals in the body that cause the penis to become erect. When taking Sildenafil Citrate 100mg Tablets, the effects of the chemical in the body may be increased.
The medicine works by increasing the blood flow to the penis during sexual stimulation. This results in the erection in a man that is more sensitive to sexual stimulation. Sildenafil Citrate 100mg Tablets is a safe and effective treatment for erectile dysfunction, which is due to the increase in blood flow to the penis during sexual stimulation. However, it may cause side effects such as headache, nausea, flushing, dizziness, or blurred vision. If you experience any side effects, you should stop taking this medicine and seek medical attention. Consult your doctor immediately if you have any of the following side effects: headache; back pain; muscle pain; nausea; dizziness; or visual changes in one or both eyes.
You should not use this medicine if you have a history of heart disease, high or low blood pressure, severe liver or kidney disease, or if you have taken an MAO inhibitor such as ketoconazole or itraconazole. MAO inhibitors include:
If you have any of these side effects, you should stop taking this medicine and seek medical attention.
Sildenafil Citrate 100mg Tablets is an orally disintegrating tablet, taken by mouth. The medicine is available in the form of a tablet or a disintegrating pack that is easy to swallow. It contains 100 mg of Sildenafil Citrate and is available in various strengths and dosages. It is important to take Sildenafil Citrate 100mg Tablets at least 1 hour before sexual activity. It can help you to achieve and maintain an erection.Do not take this medicine if you have recently taken nitrate-containing medications, as this may cause an unsafe drop in blood pressure.
It is not recommended to take this medicine more than once a day. You should not take it more than once a day. Taking more than the recommended dose of Sildenafil Citrate 100mg Tablets may increase the risk of side effects.
If you are allergic to Sildenafil Citrate 100mg Tablets or any of the ingredients of this medicine, you should not take this medicine. You should consult your doctor immediately if you experience severe side effects or an allergic reaction.